COVID-19: Mouthwash can kill coronavirus within 30 seconds, study finds

Tuesday 17th November 2020 10:00 GMT

The preliminary findings, which are yet to be peer reviewed, come ahead of a clinical trial investigating whether over-the-counter mouthwash can reduce the levels of coronavirus in a patient's saliva.

The research, which was conducted at Cardiff University, found that mouthwashes containing 0.07% of the ingredient cetylpyridinium chloride (CPC) showed "promising signs" of reducing COVID-19.

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These findings support another recently published study which identified that CPC-based mouthwashes are effective in reducing the viral load of coronavirus.

Scientists conducted tests in a laboratory mimicking the conditions of a person's nasopharynx and oropharynx passages, using mouthwash brands such as Dentyl.

Reserachers say Venture Life Group, which makes Dentyl, provided information to the study but did not fund it. The same company will fund the next stage of research.

A 12-week clinical trial at the University Hospital of Wales will now help determine the effectiveness of mouthwash in reducing the COVID-19 viral load in patients' saliva.

The findings will be published in early 2021.

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Professor David Thomas, from Cardiff University who is leading the clinical trial, said: "Although this in vitro study is very encouraging and is a positive step, more clinical research is now clearly needed.

"We need to understand if the effect of over-the-counter mouthwashes on the COVID-19 virus achieved in the laboratory can be reproduced in patients, and we look forward to completing our clinical trial in early 2021."

Dr Nick Claydon, a specialist periodontist, said the research was "very valuable".

He said: "If these positive results are reflected in Cardiff University's clinical trial, CPC-based mouthwashes such as Dentyl used in the in vitro study could become an important addition to people's routine, together with handwashing, physical distancing and wearing masks, both now and in the future."

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